Bacteriophage T4 has two sets of tail fibers, long tail fibers that are the initial receptor binding proteins and short tail fibers that bind subsequently and trigger the infection process including: an opening of the base of the tail, contraction of the outer sheath. Bacteriophage T4 has two sets of tail fibers, long tail fibers that are the initial receptor binding proteins and short tail fibers that bind subsequently and trigger the infection process including: an opening of the base of the tail, contraction of the outer sheath. In this paper, we introduce RBPseg, a method that combines monomeric 23 ESMfold predictions with a novel sigmoid distance pair (sDp) protein segmentation technique. These segments are then predicted in parallel using AF2M and assembled into a 26 full fiber model. We demonstrate that. Order of dsDNA bacteriophages with an external tail structure. Includes the Podoviridae, Siphoviridae and Myoviridae. Also includes the type VI secretion system, R-type pyocins, the. Tail fibers, a major class of RBPs, are elongated and flexible trimeric proteins, making their full-length structures difficult to resolve experimentally. Advances in deep learning–based protein structure prediction, such as AlphaFold2-multimer (AF2M) and ESMFold, provide opportunities for studying. At the far end of the tail are one or more receptor binding proteins (the tail fibers), also described as adhesins.